By Gérard Jaouen, Michèle Salmain
An up to date reference reflecting the numerous advances and significant breakthroughs made during this rising self-discipline during the last decade.
As such, the ebook presents an summary of the most recent advancements and destiny developments within the box, targeting such purposes because the improvement of probably energetic organometallic medicinal drugs opposed to incurable illnesses, in addition to in such components as catalysis, strength, analytical chemistry, and imaging.
The popular editor, who confirmed the time period "bioorganometallics", and his overseas workforce of specialists have prepare a worthwhile source for researchers in organometallic, inorganic, medicinal, and biochemistry.
Read or Download Bioorganometallic Chemistry: Applications in Drug Discovery, Biocatalysis, and Imaging PDF
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Extra resources for Bioorganometallic Chemistry: Applications in Drug Discovery, Biocatalysis, and Imaging
Moving beyond therapeutic uses, the metal ions present in organometallic complexes can be tracked by various analytical methods, making them valuable diagnostic tools. We are optimistic that the various advantages that organometallic compounds yield will soon lead to new exciting advances in the ﬁeld of medicinal chemistry and chemical biology. ), the Stiftung für wissenschaftliche Forschung of the University of Zurich, and the University of Zurich. We thank Dr. Daniel Can and Prof. 26. We also thank Prof.
Among the different elements of the periodic table, potential dual candidates are 64 Cu-67 Cu, 123 I 131 I, and 86 Y 90 Y. Note that due to their comparable chemical behaviors, 111In and the more “exotic” 177Lu have been proposed as alternatives to 90 Y due to the high-radiation energy of the latter. However, an important drawback of these duos is the production of the radioisotopes. A synchrotron is indeed required. A more favorable option is the use of the 99m Tc-188 Re matched pair. The 99m Tc radioisotope has ideal radionuclear properties for diagnostic purposes and is available from a commercial 99 Mo=99m Tc generator.
51, 4790–4795. , and 37 38 1 Organometallic Complexes as Enzyme Inhibitors: A Conceptual Overview 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 Filipovska, A. (2008) J. Am. Chem. , 130, 12570–12571. E. and Benesch, R. (1955) J. Am. Chem. , 77, 5877–5881. E. S. (1967) Arch. Biochem. , 122, 164–173. , and Ott, I. (2011) J. Med.