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By John Butterfield; David Honigmann; P Parker

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Suggested Sources Lumb AB. Nunn’s applied respiratory physiology. 6th ed. Philadelphia: Elsevier Butterworth Heinemann; 2005. West JB. Respiratory physiology – the essentials. 7th ed. Philadelphia: Lippincott Williams & Wilkins; 2005. Chapter 3 Respiratory Pathophysiology Shannon S. McKenna Keywords Respiratory pathophysiology • Obstructive pulmonary disease • Restrictive pulmonary disease • Pulmonary vascular disease Introduction The enormous topic of respiratory disease may be functionally organized, for the purposes of this manual, into the following general categories: ■ Obstructive pulmonary disease ■ Restrictive pulmonary disease ■ Pulmonary vascular disease Obstructive Disease Definition The key feature of obstructive lung disease is increased resistance to air flow.

Suggested Sources Lumb AB. Nunn’s applied respiratory physiology. 6th ed. Philadelphia: Elsevier Butterworth Heinemann; 2005. West JB. Respiratory physiology – the essentials. 7th ed. Philadelphia: Lippincott Williams & Wilkins; 2005. Chapter 3 Respiratory Pathophysiology Shannon S. McKenna Keywords Respiratory pathophysiology • Obstructive pulmonary disease • Restrictive pulmonary disease • Pulmonary vascular disease Introduction The enormous topic of respiratory disease may be functionally organized, for the purposes of this manual, into the following general categories: ■ Obstructive pulmonary disease ■ Restrictive pulmonary disease ■ Pulmonary vascular disease Obstructive Disease Definition The key feature of obstructive lung disease is increased resistance to air flow.

Radiology in the intensive care unit (part 2). J Intensive Care Med. 2003b;18(5):239–52. Jacobson FL. Chest imaging: role of CT, PET/CT, and MRI. In: Sugarbaker DJ, editor. Adult chest surgery. New York: McGraw-Hill; 2009. p. 19–34. Chapter 3. Chapter 2 Respiratory Physiology Michael Nurok and George P. Topulos Keywords Respiratory system • Ventilation • Inspiration • Expiration • Pleural and transmural pressure • Lung volumes • FEV1 • FRC • Functional residual capacity • Hysteresis • Diffusing • Diffusing capacity • Miget diagrams • Hypoxic pulmonary vasoconstriction Introduction The primary function of the respiratory system is to exchange carbon dioxide and oxygen in order to support metabolism.

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