Download Cellular and Molecular Immunology (7th Edition) by Abul K. Abbas, Shiv Pillai, Andrew H. H. Lichtman PDF

By Abul K. Abbas, Shiv Pillai, Andrew H. H. Lichtman

Mobile and Molecular Immunology takes a complete but basic method of the newest advancements during this lively and fast-changing box. Drs. Abul ok. Abbas, Andrew H. Lichtman, and Shiv Pillai current sweeping updates during this new version to hide antigen receptors and sign transduction in immune cells, mucosal and pores and skin immunity, cytokines, leukocyte-endothelial interplay, and extra. In print and on-line with extra assets, this reference is the up to date and readable textbook you must grasp the complicated topic of immunology.

• realize the medical relevance of the immunology via discussions of the consequences of immunologic technology for the administration of human disease.

• grab the main points of experimental observations that shape the foundation for the technology of immunology on the molecular, mobile, and whole-organism degrees and draw the best conclusions.

• remain abreast of the newest advances in immunology and molecular biology via huge updates that disguise cytokines, innate immunity, leukocyte-endothelial interactions, signaling, costimulation, and more.

• Visualize immunologic strategies extra successfully via a totally revised paintings software with redrawn figures, a brighter colour palette, and extra three-d art.

• locate info extra fast and simply via a reorganized bankruptcy constitution and a extra logical circulate of fabric.

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Additional resources for Cellular and Molecular Immunology (7th Edition)

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Schultze, unpublished). Similarly, the newly identified apoptosis inhibitor protein survivin has been recognized as a widely occurring tumor-associated antigen capable of inducing cytolytic specific CD8+ T cells in vitro [24, 47]. At least one peptide predicted by epitope deduction was shown to result from natural intracellular processing of survivin. 9 Prospect of Universal Tumor Antigens as a Clinical Target for Immunotherapy There are several reasons to consider that universal tumor-associated antigens, characterized by epitope deduction might offer a useful advance in the development of cellular immunotherapy.

Index TICD see tumor-induced cell death TILNs see tumor-infiltrated lymph nodes TILs see tumor-infiltrating lymphocytes TIMP see tumor inhibitor of metalloproteinase TLR family, PRR receptors 271 f. TNF see tumor necrosis factor TNF-a ±, dendritic cells 184 f. ±, MHC class I antigens 79 TNF-related activation induced cytokine receptor (TRANCE-R) 181 tolerance ±, central 211, 223 ±, immunobiological 206 f. ±, peripheral 263 toll-like receptors, dendritic cells 180 total body radiation 299 toxin moiety, immunotoxins 351 toxins ±, bacterial see bacterial toxins ±, chimeric see chimeric toxins ±, Coley's see Coley's toxins ±, diphteria see diphteria toxin ±, endo- see endotoxins ±, exo- see pseudomonas exotoxin ±, immuno- see immunotoxins ±, lympho- see lymphotoxins TRAIL-TRAIL receptor pathway, tumor microenvironment 112 TRANCE-R see TNF-related activation induced cytokine receptor transferrin receptor 361 transforming growth factor (TGF) 100 transforming growth factor (TGF)-b 119±125 ±, effects of IL-10 165 f.

R. and Greenberg, P. D. Melanocyte destruction after antigen-specific immunotherapy of melanoma: direct evidence of T cell-mediated vitiligo, J Exp Med 192: 1637±44, 2000. 7 Schultze, J. , Anderson, K. , Gilleece, M. , Gribben, J. G. and Nadler, L. M. A pilot study of combined immunotherapy with autologous adoptive tumour-specific T-cell transfer, vaccination with CD40-activated malignant B cells and interleukin 2, Br J Haematol 113: 455±60, 2001. 8 Rosenberg, S. ,Yang, J. , Schwartzentruber, D.

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