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By Gary G. Meadows

A special e-book at the interactions and interrelationships among tumor and host that modulate development and metastasis. a number of authors emphasize focusing on the host instead of the tumor itself for healing intervention to regulate melanoma.

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Extra resources for Integration Interaction of Oncologic Growth (Cancer Growth and Progression)

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2000, A confirmatory prognostic study on oxygenation status and loco-regional control in advanced head and neck squamous cell carcinoma treated by radiation therapy. Radiother Oncol, 57:39-43. , and Feldmann, H. , 2001, Predictive value of the tumor oxygenation by means of pO2 histography in patients with advanced head and neck cancer. Strahlenther Onkol, 177:462-468. 48. 49. 50. 51. 52. 53. 54. 55. 56. 57. , Evensen, J. , Rofstad, E. , 1997, Correlation of high lactate levels in head and neck tumors with incidence of metastasis.

Daly, J. , Zlatkin, M. , Frank, T. , Holland, G. , and Kressel, H. , 1991, Integrated magnetic resonance imaging and phosphorus spectroscopy of soft tissue tumors. Cancer, 67:1849-1858. van de Merwe, S. , van den Berg, A. , Kroon, B. , van den Berge, A. , Klaase, J. , 1993, Modification of human tumour and normal tissue pH during hyperthermic and normothermic antiblastic regional isolation perfusion for malignant melanoma: a pilot study. Int J Hyperthermia, 9:205-217. , Leeper, D. , Cater, J.

K good prognosis, L poor prognosis, ҟ no effect. Listed are recent studies or recent review articles. The list is not comprehensive, and the exact definition of the end-points might vary from study to study. Gene ID Gene name Tumour type Reference ANG AMF bFGF Angiogenin Autocrine motility factor Basic fibroblast growth factor CA IX Carbonic anhydrase IX CA XII CatB CXCR4 Glut-1 Carbonic anhydrase XII Cathepsin B C-X-C receptor type 4 Glucose transporter-1 HIF-1α Hypoxia-inducible factor-1α IL-8 Interleukin-8 ILK c-MET MMP-9 Integrin-linked kinase OPN Osteopontin PAI-1 Plasminogen activator inhibitor-1 Platelet derived endothelial cell growth factor PD-ECGF TIMP-1 uPAR VEGF Matrix metalloproteinase-9 Tissue inhibitor of metalloproteinase-1 Urokinase type plasminogen activator receptor Vascular endothelial growth factor BladderL, breastL and pancreaticL LungL BladderL, breastK−, colorectalL−, gastricL, head and neckL−, hepatocellularL, lungL−, ovarianLK and pancreaticL BreastL, cervicalLK−, head and neckL−, nasopharyngeal−, non-small-cell lungL and renal clear cellK BreastLK Breast−, non-small-cell lungL and ovarianL Clear renal cellL and non-small-cell lungL BladderL, cervicalL, colorectalL, gastricL, non-small-cell lungL, ovarianL and rectalL Breast↓, cervical↓−, endometrial↓, head and neck↓↑, nasopharyngeal−, non-small-cell lung−↑, oropharyngeal↓, ovarian− and oligodendroglioma↓ hepatocellular↓, melanoma↓ , non-small-cell lung↓ and ovarian↓ MelanomaL BreastL and prostateL ColorectalL, gastricL, head and neckL, lungL, non-smallcell lungL and ovarianL BreastL, colorectalL, head and neckL, hepatocellularL, lungL and prostateL BreastL, cervicalL, gastricL and lungL−, ovarianL, renal cellL, BladderL, breastL, colorectalLK−, gastricL, head and neckL, hepatocellularL−, lungL, ovarianL and pancreaticL BladderL, breastL, colorectalL, gastricL, prostateLK and lungL BladderL, breastL−, colorectalL, endometrial−, hepatocellularL, non-small-cell lung−, ovarian−, renal cellL, squamous cell lungL and chondrosarcomaL BladderL−, breastL, colorectalL, gastricL−, head and neckL−, hepatocellularL−, lungL, pancreaticL, prostateL, ovarianL, melanomaL and osteosarcomaL 123 124 123 125-128 129 130-132 92,133 125,126 80,125 134-137 138 139 140 141 142,143 123 144,145 146 123 1.

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